Rat Somatostatin, SS ELISA KI
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[Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin. [Neuronostatin]: May enhance low-glucose-induced glucagon release by pancreatic alpha cells (PubMed: 24735892). This effect may be mediated by binding to GPR107 and PKA activation (PubMed: 26561648). May regulate cardiac contractile function (PubMed: 22170057). May compromise cardiomyocyte viability (PubMed: 22170057). In the central nervous system, may impair memory retention and may affect hippocampal excitability (PubMed: 21978882). May also have anxiolytic and anorexigenic effects (PubMed: 18753129, PubMed: 21978882). May play a role in arterial pressure regulation (PubMed: 18753129, PubMed: 21978882). May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH (By similarity). Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Cell culture supernatants | Ascites | Tissue homogenates |
|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
SST identifies somatostatin in Homo sapiens (Human). This target record connects NCBI Gene 6750, UniProtKB P61278 and related ABMIUM catalogue products.
