AMACR Monoclonal Antibody(4A12)
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N/A
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | IF | IHC | WB | ICC | IHC-p |
|---|---|---|---|---|---|
| Applications |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AMACR (alpha-methylacyl-CoA racemase; P504S) is a mitochondrial and peroxisomal enzyme that interconverts stereoisomers of alpha-methyl branched acyl-CoA substrates. It is studied in branched-chain fatty-acid oxidation, bile-acid intermediate metabolism and metabolic enzyme expression research.
Biological function: Alpha-methylacyl-CoA racemase converts (2R)-2-methylacyl-CoA esters to the (2S) configuration required for downstream beta-oxidation. Human AMACR acts on substrates derived from branched-chain fatty acids such as pristanic acid and on bile-acid synthesis intermediates, linking peroxisomal and mitochondrial lipid metabolism.
