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Anticorps anti-CA12 humain [A1033]
SKU: ABM635Anticorps Primaires
- Target
- CA12
- Reactivity
- Humain
- Applications
- ICC/FI
- Host
- Souris
£190.40£238.00
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carbonic anhydrase 12
Carbonic anhydrase 12 (CA12; carbonic anhydrase XII/CA-XII) is a type I transmembrane zinc metalloenzyme with an extracellular catalytic domain. It is studied in epithelial CO2/bicarbonate handling, extracellular pH regulation and tissue-specific membrane carbonic-anhydrase biology.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
CA12 catalyses reversible hydration of carbon dioxide at the cell surface, generating bicarbonate and protons and contributing to extracellular acid-base handling. Its transmembrane localisation links carbonic-anhydrase catalysis to epithelial transport and pH-regulatory systems.
CA12 research includes epithelial bicarbonate and fluid handling, membrane pH regulation, kidney and secretory-tissue physiology, and context-dependent altered expression in selected tumour systems. Expression observations should not be interpreted as universal diagnostic or therapeutic claims.
Names used across publications, databases and supplier catalogues.