Manufactured by:ProteoGenix
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Recombinant Human BCAS2 Protein, N-His

Recombinant Human BCAS2 Protein, N-His from ProteoGenix; catalogue ARO-P11900; research use only.

SKU:
ABM142339-1
Manufacturer SKU
ARO-P11900
Product type
Recombinant Proteins
Expression systemProkaryotic expression

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Recombinant proteins have become essential tools in various fields of research and medicine. These proteins are produced through genetic engineering techniques, where a specific gene is inserted into a host organism to produce large quantities of the desired protein. One such protein is the Recombinant Human BCAS2 Protein, which has gained attention for its unique structure, diverse activity, and potential applications.

Structure of Recombinant Human BCAS2 Protein

The BCAS2 gene encodes for a 401 amino acid protein, which is highly conserved among different species. The recombinant version of this protein is produced in E. coli or mammalian cells, with a molecular weight of approximately 45 kDa. The protein consists of several functional domains, including a nuclear localization signal, a transcriptional activation domain, and a DNA-binding domain. These domains play a crucial role in the protein’s activity and function.

Activity of Recombinant Human BCAS2 Protein

Recombinant Human BCAS2 Protein has been shown to have diverse activities in various cellular processes. One of its main functions is its role as a transcriptional coactivator, where it interacts with other proteins to enhance gene expression. It has also been reported to regulate cell proliferation and differentiation by modulating the activity of key signaling pathways, such as the Wnt/β-catenin pathway. Furthermore, studies have shown that BCAS2 plays a crucial role in DNA damage response and repair, making it a potential target for cancer therapy.

Application of Recombinant Human BCAS2 Protein

The unique structure and diverse activity of Recombinant Human BCAS2 Protein make it a valuable tool in various research and medical applications. One of its main uses is in studying gene regulation and transcriptional control. The protein’s ability to enhance gene expression makes it a useful tool in understanding the mechanisms of gene regulation and identifying potential therapeutic targets.

Moreover, Recombinant Human BCAS2 Protein has been studied for its potential role in cancer therapy. Its involvement in DNA damage response and repair pathways makes it a promising target for developing new treatments for cancer. Additionally, BCAS2 has been linked to drug resistance in certain types of cancer, making it a potential biomarker for predicting treatment response.

Furthermore, Recombinant Human BCAS2 Protein has been used in the development of diagnostic assays for various diseases. Its interaction with other proteins and its role in cell signaling pathways make it a potential biomarker for different diseases, including cancer and neurodegenerative disorders.

Conclusion

In summary, Recombinant Human BCAS2 Protein has a unique structure, diverse activity, and potential applications in various fields of research and medicine. Its role as a transcriptional coactivator, regulator of cell proliferation and differentiation, and involvement in DNA damage response and repair make it a valuable tool in understanding gene regulation and developing new treatments for diseases. With ongoing research and advancements in genetic engineering techniques, the use of Recombinant Human BCAS2 Protein is expected to expand, further contributing to the advancement of science and medicine.

ProteoGenix catalogue number ARO-P11900. For research use only.

Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 28.29 kDa; Fragment: Met1-Phe225; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
DNA amplified in mammary carcinoma 1 protein, BCAS2, DAM1, Breast carcinoma-amplified sequence 2, Pre-mRNA-splicing factor SPF27, Spliceosome-associated protein SPF 27
Host species
E. coli
Source organism
Human
Molecular weight
28.29 kDa
Sequence fragment
Met1-Phe225
Sequence
MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF
Technical note
For research use only.
Identifiers & database references
Manufacturer SKU
ARO-P11900
UniProt accession
O75934
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Shipped at
Dry Ice
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
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