CD40 Recombinant Protein from ProteoGenix; catalogue PX-P4082; research use only.
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CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily, which is a single transmembrane glycoprotein. The CD40 protein plays a vital role in mediating a variety of immune and inflammatory responses, including the change in class T that depends on the type of immunoglobulin, the development of B cell memory and the formation of reproductive centers. The CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells and some tumor cells. CD40 deficiency can lead to high IgM type 3 (HIGM3) immunodeficiency. In addition, β-amyloid-induced microglia activation requires CD40 / CD40L interaction and is therefore considered an early event in the pathogenesis of Alzheimer’s disease.
ProteoGenix catalogue number PX-P4082. For research use only.
Host: Mammalian cells; Expression system: Eukaryotic expression; Purity: >90% by SDS-PAGE; Molecular weight: 22.32kDa; Tag: C-terminal His Tag; Fragment: Met1~Arg193; Buffer: PBS pH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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