Rat Adiponectin, ADIPOQ ELISA Kit
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Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Urine | Ascites | Cerebrospinal fluid | Tissue | Cell culture supernatants | Tissue homogenates |
|---|---|---|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Adiponectin, C1Q and collagen domain containing (ADIPOQ) encodes the secreted adipokine adiponectin, also known by established names including Acrp30 and GBP28. Human ADIPOQ is represented by NCBI Gene 9370 and reviewed UniProtKB Q15848, with related ABMIUM catalogue reagents for research use.
Biological function: ADIPOQ encodes adiponectin, a secreted adipokine involved in regulation of fat metabolism and insulin sensitivity. Adiponectin promotes AMPK activation in liver and skeletal muscle, supports glucose utilisation and fatty-acid oxidation, and has anti-inflammatory and anti-atherogenic activities.
