ABMIUM target intelligence
CD80 molecule
CD80 molecule (CD80), also known as B7-1 and T-lymphocyte activation antigen CD80, is an immunoglobulin-superfamily costimulatory molecule. This guide connects human NCBI Gene 941, UniProtKB P33681 and ABMIUM catalogue products associated with CD80.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
CD80 / B7-1 provides an important costimulatory signal for T-lymphocyte activation by acting as a ligand for CD28, augmenting MHC/T-cell receptor signalling. CD80 also binds CTLA-4, which can oppose CD28-mediated priming and limit T-cell activation, placing CD80 at a key immune costimulation and checkpoint interface.
CD80 / B7-1 is commonly studied in antigen-presenting-cell biology, T-cell costimulation, CD28 and CTLA-4 signalling, humoral immunity and immune-oncology models. Use the catalogue filters below to compare ABMIUM CD80 research products and confirm species, assay format, application and product-level validation before use.
Names used across publications, databases and supplier catalogues.
