Home » PAI-1 / SERPINE1 Antibodies & Reagents | ABMIUM

ABMIUM target intelligence

SERPINE1

serpin family E member 1

Serpin family E member 1 (SERPINE1), commonly called plasminogen activator inhibitor 1 (PAI-1), is a serine-protease inhibitor. This ABMIUM record links human SERPINE1 (NCBI Gene 5054; UniProt P05121) to catalogue-backed research products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene5054 UniProtP05121

SERPINE1 products

Need help?Ask a scientist
Loading… products
Comparing

Research context & evidence

About SERPINE1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

SERPINE1/PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), making it an important inhibitor of fibrinolysis. Curated records also describe a role in innate antiviral immunity.

Experimental context

Research context

SERPINE1, PAI-1 and plasminogen activator inhibitor 1 are widely studied in fibrinolysis, thrombosis, vascular biology and extracellular protease regulation. Confirm product-level species, application and validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

PAI1Plasminogen activator inhibitor 1PAIPLANH1PAI1APai1aaPlanhRATPAI1AMr1