ABMIUM target intelligence
activating transcription factor 2
Activating transcription factor 2 (ATF2), also known as CREB-2 and cyclic AMP-dependent transcription factor ATF-2, is a bZIP transcription factor that integrates CRE/AP-1 transcription with cellular stress and DNA-damage responses. Human ATF2 maps to NCBI Gene 1386 and reviewed UniProtKB P15336; this record links the verified target to related ABMIUM catalogue products.
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Research context & evidence
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ATF2 is a transcriptional activator that binds CRE or AP-1 response elements depending on its dimerization partner. Curated annotations support roles in gene-expression control and DNA-damage responses, with stress-regulated transcriptional activity and subcellular localization.
ATF2 is studied in CRE/AP-1 transcription, stress-activated signalling, DNA-damage responses, chromatin regulation and stimulus-dependent cell fate. Select related ABMIUM products only after confirming species, sample type, assay/application and product-level validation.
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