ABMIUM target intelligence
apolipoprotein A4
APOA4 encodes apolipoprotein A4; the mature protein apolipoprotein A-IV (ApoA-IV) is produced predominantly in the intestine and secreted in association with chylomicron particles.
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Research context & evidence
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NCBI describes apolipoprotein A-IV as an intestine-derived secreted apolipoprotein associated with chylomicrons and a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. Its precise physiological function is not fully defined.
APOA4 is studied in intestinal lipid absorption and transport, chylomicron biology, HDL-related lipid metabolism and LCAT regulation. Interpret findings according to sample type, lipoprotein context, species and product-specific validation.
Names used across publications, databases and supplier catalogues.