ABMIUM target intelligence
actinin alpha 1
Actinin alpha 1 (ACTN1), encoding alpha-actinin-1, is a non-muscle cytoskeletal actin-binding protein. This target record connects human NCBI Gene 87, reviewed UniProtKB P12814 and related ABMIUM catalogue products.
Read full target overview![Anti-Human/Mouse/Rat ACTN1 Antibody [1D4]](http://www.abmium.com/cdn/shop/files/S84qH8.jpg?v=1788967418&width=520)
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Alpha-actinin-1, encoded by ACTN1 (actinin alpha 1), is an F-actin cross-linking protein that helps anchor actin filaments to intracellular structures. In non-muscle cells it contributes to microfilament bundles and adherens-type junctions; reviewed UniProt also curates an IGSF8-associated role in immune-synapse formation and efficient T-cell activation.
ACTN1 research spans actin-cytoskeleton architecture, cell adhesion, junctional organisation, cell motility, platelet biology and immune-synapse signalling. ABMIUM catalogue products associated with ACTN1 can support target-focused studies; confirm species, sample type, application and reagent-level validation before use.
Names used across publications, databases and supplier catalogues.
