Photosensitive drug used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals and high-molecular-weight crosslinked oligomers. Independent of light exposure, verteporfin inhibits transcription by YAP/TAZ (via disruption of...
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Photosensitive drug used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals and high-molecular-weight crosslinked oligomers. Independent of light exposure, verteporfin inhibits transcription by YAP/TAZ (via disruption of YAP-TEAD interaction)(IC50 = 2.5 µM), inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines. Inhibits autophagosome formation. Reverses differentiation of Src-overexpressing embryonic stem cells, and blocks SARS-CoV-2 infection in vitro and in vivo
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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