UCPH-101 is a potent (IC50 = 660 nM) and selective inhibitor of the excitatory amino acid transporter 1 (EAAT1). It induced cell death in glioblastoma cells via intracellular glutamate accumulation. UCPH-101 also significantly increased survival in glioma-bearing mice
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UCPH-101 is a potent (IC50 = 660 nM) and selective inhibitor of the excitatory amino acid transporter 1 (EAAT1). It induced cell death in glioblastoma cells via intracellular glutamate accumulation. UCPH-101 also significantly increased survival in glioma-bearing mice
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SLC1A3 identifies solute carrier family 1 member 3 in Homo sapiens (Human). This target record connects NCBI Gene 6507, UniProtKB P43003 and related ABMIUM catalogue products.
