Manufactured by:TriBio Science
RUO

Tranilast, NFkB inhibitor

Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE 2 , IC 50 = 1-20 µM; TXB 2 , IC 50 = 10-50 µM; TGFβ1, IC 50 = 100-200 µM; IL-8, IC 50 = 100 µM). Tranilast also...

SKU:
ABM148876-1
Manufacturer SKU
TBI2234-10MG | TBI2234-50MG
Product type
Biochemical Inhibitors
TargetNFkB
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE 2 , IC 50 = 1-20 µM; TXB 2 , IC 50 = 10-50 µM; TGFβ1, IC 50 = 100-200 µM; IL-8, IC 50 = 100 µM). Tranilast also displays anti-angiogenic properties

Key facts & specifications
Also known as
Rizaben; SB252218; 3,4-DAA
Molecular weight
327.34
Form / buffer
powder
Activity
Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE 2 , IC 50 = 1-20 µM; TXB 2 , IC 50 = 10-50 µM; TGFβ1, IC 50 = 100-200 µM; IL-8, IC 50 = 100 µM). Tranilast also displays anti-angiogenic properties.
Molecular formula
C 18 H 17 NO 5
Solubility
Soluble in DMSO (up to 25 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI2234-10MG | TBI2234-50MG
CAS number
53902-12-8
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£65.00