TO1-3PEG-Desthiobiotin is a small bifunctional fluorophore that allows for the recovery of native RNA complexes while simultaneously rendering them highly fluorescent. The bound fluorescent complex of Mango I and TO1-3PEG-Desthiobiotin is bright and when bound next generation aptamers (Mango III...
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TO1-3PEG-Desthiobiotin is a small bifunctional fluorophore that allows for the recovery of native RNA complexes while simultaneously rendering them highly fluorescent. The bound fluorescent complex of Mango I and TO1-3PEG-Desthiobiotin is bright and when bound next generation aptamers (Mango III and IV) have a brightness that exceeds that of enhanced GFP. When bounded to steptavidin, can be eluted by the addition of free biotin allowing for the recovery of complexes that can be further purified (i.e. size chromatography)
The TO dye has a number of other desirable properties including:
TO1-biotin is the standard variety of TO dye for in vitro and in vivo RNA Mango and RNA Peach experiments
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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