Manufactured by:TriBio Science
RUO

TM-2-51, HDAC8 activator

Highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. Rescues the activity of catalytically compromised HDAC8 mutants in vitro

SKU:
ABM148859-1
Manufacturer SKU
TBI1522-10MG | TBI1522-50MG
Product type
Biochemical Inhibitors
TargetHDAC8
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. Rescues the activity of catalytically compromised HDAC8 mutants in vitro

Key facts & specifications
Also known as
1-Benzoyl-3-phenyl-2-thiourea
Molecular weight
256.32
Form / buffer
Powder
Activity
Highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. Rescues the activity of catalytically compromised HDAC8 mutants in vitro.
Molecular formula
C 14 H 12 N 2 OS
Solubility
Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI1522-10MG | TBI1522-50MG
CAS number
4921-82-8
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

HDAC8histone deacetylase 8

View target guide

HDAC8 identifies histone deacetylase 8 in Homo sapiens (Human). This target record connects NCBI Gene 55869, UniProtKB Q9BY41 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
55869
UniProtKB
Q9BY41
TriBio Science
£82.00