Manufactured by:TriBio Science
RUO

RVX-208, BET bromodomain inhibitor

RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis

SKU:
ABM148688-1
Manufacturer SKU
TBI1487-25MG | TBI1487-5MG
Product type
Biochemical Inhibitors
TargetBET bromodomain
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis

Key facts & specifications
Also known as
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone
Molecular weight
370.41
Form / buffer
powder
Activity
RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis.
Molecular formula
C 20 H 22 N 2 O 5
Solubility
Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI1487-25MG | TBI1487-5MG
CAS number
1044870-39-4
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£445.00