Selective inhibitor of plasma kallikrein (PLK) (Ki = 0.81 µM) that attenuates arthritis and renal damage in rats with adjuvant-induced arthritis. Its combination with NO donor GSNO in blood samples led to strong platelet inhibition and thrombolysis. Blocked PLK-dependent TGF-β activation and...
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Selective inhibitor of plasma kallikrein (PLK) (Ki = 0.81 µM) that attenuates arthritis and renal damage in rats with adjuvant-induced arthritis. Its combination with NO donor GSNO in blood samples led to strong platelet inhibition and thrombolysis. Blocked PLK-dependent TGF-β activation and significantly reduced hepatic apoptosis and mortality in a mouse model of acute liver injury
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