H+,K+-ATPase inhibitor (IC 50 = 5.8 μM). Clinically useful antisecretory and antiulcer agent. Potent inhibitor of CYP2C19 (Ki=3.1 mM). Inhibits swelling-dependent chloride channels. Facilitates oral bioavailability of bioactive peptides such as oxytocin by raising stomach pH. Displays broad...
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H+,K+-ATPase inhibitor (IC 50 = 5.8 μM). Clinically useful antisecretory and antiulcer agent. Potent inhibitor of CYP2C19 (Ki=3.1 mM). Inhibits swelling-dependent chloride channels. Facilitates oral bioavailability of bioactive peptides such as oxytocin by raising stomach pH. Displays broad spectrum antiviral activity. Enhances efficacy of remdesivir (10-fold)
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