Manufactured by:TriBio Science
RUO

Nutlin-3, p53/mdm2 inhibitor

MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells

SKU:
ABM147464-1
Manufacturer SKU
TBI1350-25MG | TBI1350-5MG
Product type
Biochemical Inhibitors
Targetp53/mdm2
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells

Key facts & specifications
Also known as
(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
Molecular weight
581.51
Form / buffer
powder
Activity
MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells.
Molecular formula
C 30 H 30 Cl 2 N 4 O 4
Solubility
Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI1350-25MG | TBI1350-5MG
CAS number
548472-68-0
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£654.00