Indazole-3-carboxylic acid derivative that inhibits mitochondria-bound hexokinase, reducing aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells (IC50 = 90 and 45 µM, respectively). Causes intracellular acidification by inhibition of lactate transport. Also inhibits the mitochondrial...
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Indazole-3-carboxylic acid derivative that inhibits mitochondria-bound hexokinase, reducing aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells (IC50 = 90 and 45 µM, respectively). Causes intracellular acidification by inhibition of lactate transport. Also inhibits the mitochondrial pyruvate carrier (Ki 2.5 μM) and monocarboxylate transporter isozymes, as well as the succinate-ubiquinone reductase activity of respiratory complex II. Enhances infection by oncolytic M1 virus via downregulation of antiviral immune response
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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