A nucleoside analog reverse transcriptase inhibitor. A potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2). Displays anti-inflammatory effects, including reduction of inflammasome-related proteins P2X7 and NLRP3, in retinal microvascular endothelial...
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A nucleoside analog reverse transcriptase inhibitor. A potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2). Displays anti-inflammatory effects, including reduction of inflammasome-related proteins P2X7 and NLRP3, in retinal microvascular endothelial cells treated with high glucose and LPS as well as in streptozotocin diabetic mice. Disrupts repeat element life cycle in colorectal cancer
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