A KCNQ2/Q3 (Kv7.2/7.3) activator, EC50=0.38 μM (KCNQ1 IC50=15 μM). KCNQ3/Q5 heterodimers are not affected. Potently dampens neuronal excitability and displays anticonvulsant activity in vivo
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A KCNQ2/Q3 (Kv7.2/7.3) activator, EC50=0.38 μM (KCNQ1 IC50=15 μM). KCNQ3/Q5 heterodimers are not affected. Potently dampens neuronal excitability and displays anticonvulsant activity in vivo
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