Manufactured by:TriBio Science
RUO

GC376, 3CLpro inhibitor

GC376 inhibits the 3C protease of poliovirus with an IC50 of 1.77 µM, foot-and-mouth disease virus (FMDV) with an IC50 of 1.16 µM, and human rhinovirus (HRV) with an IC50 of 0.2 µM. It also targets the 3C-like proteases of Norwalk virus, MD145 virus, transmissible gastroenteritis virus (TGEV),...

SKU:
ABM147064-1
Manufacturer SKU
TBI5299-25MG | TBI5299-5MG
Product type
Biochemical Inhibitors
Target3CLpro
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

GC376 inhibits the 3C protease of poliovirus with an IC50 of 1.77 µM, foot-and-mouth disease virus (FMDV) with an IC50 of 1.16 µM, and human rhinovirus (HRV) with an IC50 of 0.2 µM. It also targets the 3C-like proteases of Norwalk virus, MD145 virus, transmissible gastroenteritis virus (TGEV), and SARS-CoV, with IC50 values of 0.49 µM, 0.96 µM, 0.82 µM, and 4.35 µM, respectively

Key facts & specifications
Also known as
(βS)-α-hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid, monosodium salt
Molecular weight
507.5
Form / buffer
Powder
Activity
GC376 inhibits the 3C protease of poliovirus with an IC50 of 1.77 µM, foot-and-mouth disease virus (FMDV) with an IC50 of 1.16 µM, and human rhinovirus (HRV) with an IC50 of 0.2 µM. It also targets the 3C-like proteases of Norwalk virus, MD145 virus, transmissible gastroenteritis virus (TGEV), and SARS-CoV, with IC50 values of 0.49 µM, 0.96 µM, 0.82 µM, and 4.35 µM, respectively.
Molecular formula
C 21 H 30 N 3 O 8 S • Na
Solubility
Soluble in DMSO (10 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI5299-25MG | TBI5299-5MG
CAS number
1416992-39-6
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£263.00