Reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease. Displays neurotrophic effects, enhancing the formation of dendritic filopodia and inducing a network of F-actin-containing neurites in cultured hippocampal neurons. Promotes the...
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Reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease. Displays neurotrophic effects, enhancing the formation of dendritic filopodia and inducing a network of F-actin-containing neurites in cultured hippocampal neurons. Promotes the survival of cultured central nervous system neurons possibly by opening mitochondrial KATP channels. Displays neuroprotective effects in a rat model of acute retinal ischemia
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