Potent inhibitor of HMG-CoA reductase, IC50=40-100 nM. Clinically useful, orally active antihypercholesterolemic agent. Inhibits vascular smooth muscle proliferation, IC50=70 nM. Displays antineuroinflammatory activity. Prevents lung adenocarcinoma bone metastasis by triggering autophagy....
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Potent inhibitor of HMG-CoA reductase, IC50=40-100 nM. Clinically useful, orally active antihypercholesterolemic agent. Inhibits vascular smooth muscle proliferation, IC50=70 nM. Displays antineuroinflammatory activity. Prevents lung adenocarcinoma bone metastasis by triggering autophagy. Attenuates cell proliferation in hepatocellular carcinoma
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