The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is a receptor tyrosine kinase critical for regulating cell proliferation, differentiation, survival, migration, and organ development. Dysregulation of EGFR signaling-through mutations, overexpression, or loss-of-function, is implicated...
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The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is a receptor tyrosine kinase critical for regulating cell proliferation, differentiation, survival, migration, and organ development. Dysregulation of EGFR signaling-through mutations, overexpression, or loss-of-function, is implicated in a diverse spectrum of human diseases
Tribioscience’s Fast EGFR Kinase Activity Assay is designed to quantitatively detect EGFR Kinase Activity levels in different tissues including skin, muscle, neural, serum, and other biological samples. In this assay EGFR phosphorates tyrosine-based substrate in the presence of co-substrate ATP. The assay combines multiple reactions into a one-step. The measurement can be finished in 1.5 hours. The levels of sample EGFR Kinase activity are parallel to the standard curves obtained using the kit standards linearly. These results indicate that this kit can be used to determine relative mass values for natural EGFR Kinase Activity
Accurate: Directly measure the phorsphoration of tyrosine
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Linearity |
|---|---|
| Serum |
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
