Manufactured by:TriBio Science
RUO

E-64, Cysteine protease inhibitor

Cell-permeable, epoxysuccinyl peptide irreversible inhibitor of calpain and other cysteine proteases. Inhibits calpain-dependent apoptosis pathway in T cells but promotes heat-induced apoptosis in FM3A cells.

SKU:
ABM146962-1
Manufacturer SKU
TBI1345-25MG | TBI1345-5MG
Product type
Biochemical Inhibitors
TargetCysteine protease
Purity≥98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Cell-permeable, epoxysuccinyl peptide irreversible inhibitor of calpain and other cysteine proteases. Inhibits calpain-dependent apoptosis pathway in T cells but promotes heat-induced apoptosis in FM3A cells.

Key facts & specifications
Also known as
(2S,3S)-trans-Epoxy succinyl-L-leucylamido-(4-guanidino) butane
Molecular weight
357.41
Working concentration
0
Form / buffer
Powder
Activity
Cell-permeable, epoxysuccinyl peptide irreversible inhibitor of calpain and other cysteine proteases. Inhibits calpain-dependent apoptosis pathway in T cells but promotes heat-induced apoptosis in FM3A cells. Typical working concentration is 0.5-10 µg/ml.
Molecular formula
C 15 H 27 N 5 O 5
Solubility
Soluble in a 1:1 mixture of ethanol and water (20 mg/ml) or DMSO (25 mg/ml)
Technical note
Stability: ≥ 1 year
Identifiers & database references
Manufacturer SKU
TBI1345-25MG | TBI1345-5MG
CAS number
66701-25-5
Storage, stability & shipping
Storage conditions
-20℃
Shipped at
4°C
Long-term storage
-20℃
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£311.00