Formulation: Soln in water with 5% acetonitrile at 50 µg / 0.5 ml Domoic acid (DA), a kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia is responsible for amnesic shellfish poisoning. Suspension feeders such as bivalve mollusks can accumulate...
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Formulation: Soln in water with 5% acetonitrile at 50 µg / 0.5 ml
Domoic acid (DA), a kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia is responsible for amnesic shellfish poisoning. Suspension feeders such as bivalve mollusks can accumulate and retain high amounts of DA in their tissues, threatening human health. DA is a potent agonist at kainate and AMPA receptors and induces convulsive behavior and seizures in rodents. It induces structural and molecular changes in the developing zebra fish nervous system
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