Manufactured by:TriBio Science
RUO

Diphenylene iodonium chloride, Flavoprotein inhibitor

Diphenylene iodonium chloride, Flavoprotein inhibitor An irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively. Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase. Novel agonist for GPR3. Inhibits NFκB activation induced by IL-1β. Prevents early...

SKU:
ABM146924-1
Manufacturer SKU
TBI2668-10MG | TBI2668-50MG
Product type
Biochemical Inhibitors
TargetFlavoprotein
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Diphenylene iodonium chloride, Flavoprotein inhibitor

An irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively. Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase. Novel agonist for GPR3. Inhibits NFκB activation induced by IL-1β. Prevents early alcohol-induced liver injury in rodent models

Key facts & specifications
Also known as
DPI
Molecular weight
314.55
Form / buffer
Powder
Activity
An irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively. Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase. Novel agonist for GPR3. Inhibits NFκB activation induced by IL-1β. Prevents early alcohol-induced liver injury in rodent models.
Molecular formula
C 12 H 8 I ·Cl
Solubility
Soluble in DMSO (up to 5 mg/ml, with warming).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI2668-10MG | TBI2668-50MG
CAS number
4673-26-1
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£90.00