Full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively and also at 5HT1A and 5HT1F receptors. One of the oldest agents for treatment of migraine. Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist
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Full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively and also at 5HT1A and 5HT1F receptors. One of the oldest agents for treatment of migraine. Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist
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