A potent inhibitor of monoamine oxidase B (MAO- B) which has been used for the treatment of Parkinson’s disease. Displays neuroprotective effects rescuing nigral dopaminergic neurons after systemic MPTP treatment. Rescues PC12 cells from trophic withdrawal-induced apoptosis....
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A potent inhibitor of monoamine oxidase B (MAO- B) which has been used for the treatment of Parkinson’s disease. Displays neuroprotective effects rescuing nigral dopaminergic neurons after systemic MPTP treatment. Rescues PC12 cells from trophic withdrawal-induced apoptosis. Glyceraldehyde-3-phosphate dehydrogenase has been found to be the putative target responsible for its neuroprotective effects
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