Potent and selective β3 adrenergic receptor agonist (EC50= 3 nM). Displays anti-obesity and anti-diabetic effects in mice. It increases brown fat thermogenesis and metabolic rate and decreases blood insulin and glucose levels. Induces functionally active mitochondrial uncoupling protein (UCP) in...
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Potent and selective β3 adrenergic receptor agonist (EC50= 3 nM). Displays anti-obesity and anti-diabetic effects in mice. It increases brown fat thermogenesis and metabolic rate and decreases blood insulin and glucose levels. Induces functionally active mitochondrial uncoupling protein (UCP) in white fat. Active in vivo
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