A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process. CK-666 attenuates BBB...
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A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process. CK-666 attenuates BBB dysfunction induced by methamphetamine. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal and pathophysiology
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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