Inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50’s between 0.2 and 5.8 µM in various cell lines3 and 20 nM for isolated enzyme. Reduced leukemic cell burden, decreased levels of leukemia-initiating cells, and improved survival in human and mouse models of acute myeloid leukemia....
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Inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50’s between 0.2 and 5.8 µM in various cell lines3 and 20 nM for isolated enzyme. Reduced leukemic cell burden, decreased levels of leukemia-initiating cells, and improved survival in human and mouse models of acute myeloid leukemia. Displays broad antiviral activity against flaviviruses, positive-strand RNA alphaviruses, negative-strand RNA rhabdoviruses, Influenza A and B viruses, and HIV
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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