Manufactured by:TriBio Science
RUO

Atglistatin, ATGL inhibitor

Atglistatin is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM. It exhibits high selectivity for ATGL, is active in vitro and in vivo, and does not inhibit other key metabolic lipases. ATGL is the rate limiting enzyme in lipolysis and is thus an excellent...

SKU:
ABM146648-1
Manufacturer SKU
TBI4598-25MG | TBI4598-5MG
Product type
Biochemical Inhibitors
TargetATGL
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Atglistatin is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM. It exhibits high selectivity for ATGL, is active in vitro and in vivo, and does not inhibit other key metabolic lipases. ATGL is the rate limiting enzyme in lipolysis and is thus an excellent target to reduce fatty acid mobilization and decrease lipotoxicity in metabolic syndrome. Inhibition of ATGL may be a useful strategy to attack the increased metabolic rate of cancerous cells

Key facts & specifications
Also known as
N’-[4’-(Dimethylamino)[1,1’-biphenyl]-3-yl]-N,N,-dimethylurea
Molecular weight
283.37
Form / buffer
powder
Activity
Atglistatin is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM. It exhibits high selectivity for ATGL, is active in vitro and in vivo, and does not inhibit other key metabolic lipases. ATGL is the rate limiting enzyme in lipolysis and is thus an excellent target to reduce fatty acid mobilization and decrease lipotoxicity in metabolic syndrome. Inhibition of ATGL may be a useful strategy to attack the increased metabolic rate of cancerous cells.
Molecular formula
C 17 H 21 N 3 O
Solubility
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI4598-25MG | TBI4598-5MG
CAS number
1469924-27-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£368.00