Manufactured by:TriBio Science
RUO

Allopregnanolone, GABA-A positive allosteric modulator

Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors. Recently FDA approved (Brexanolone) for postpartum depression. Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain. Inhibits glutamate release and displays neuroprotective...

SKU:
ABM146591-1
Manufacturer SKU
TBI3489-25MG | TBI3489-5MG
Product type
Biochemical Inhibitors
TargetGABA-A positive allosteric
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors. Recently FDA approved (Brexanolone) for postpartum depression. Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain. Inhibits glutamate release and displays neuroprotective effects in various animal models

Key facts & specifications
Also known as
(3α,5α)-Tetrahydroprogesterone; 3-OH-DHP
Molecular weight
318.49
Form / buffer
powder
Activity
Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors. Recently FDA approved (Brexanolone) for postpartum depression. Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain. Inhibits glutamate release and displays neuroprotective effects in various animal models.
Molecular formula
C 21 H 34 O 2
Solubility
Soluble in DMSO (up to 32 mg/ml) or in Ethanol (up to 32 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI3489-25MG | TBI3489-5MG
CAS number
516-54-1
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
$550.00