RPL-αMan – Fucose and α-Mannose | Recombinant Prokaryotic Lectins (RPLs)

RPL-αMan – Fucose and α-Mannose | Recombinant Prokaryotic Lectins (RPLs) scientific glycan-binding protein illustration

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RPL-αMan – Fucose and α-Mannose | Recombinant Prokaryotic Lectins (RPLs)

Recombinant lectin selective for Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose.

SKU:
ABM146484
Manufacturer SKU
L-006-2mg
Product type
Recombinant Proteins
TargetFucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose
ApplicationsGlycan recognition, binding assay
Sample typePurified glycans, glycosylated proteins
Expression systemEscherichia coli

Manufacturer provenance

Manufactured by:
GlycoSeLect
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

RPL-αMan is a recombinant prokaryotic lectin with specificity for Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose. It is supplied as 2 mg at 2 mg/mL and has a monomer molecular weight of 13,130 Da.

Recombinant Prokaryotic Lectins (RPLs) are glycoselective bioaffinity compounds that recognise and bind specific glycan structures displayed on glycoproteins and other glycosylated biomolecules. They enable simple, rapid and efficient detection, analysis, separation and purification of intact glycosylated biomolecules.

GlycoSeLect developed this RPL range for glycan epitopes including terminal galactose, mannose, sialic acid and fucose structures. Every RPL carries a polyhistidine tag, enabling detection with standard conjugated anti-His antibodies without in-vitro biotinylation or other labelling.

Key characteristics

  • High glycan specificity and enhanced binding characteristics
  • Consistent recombinant quality from scalable production
  • Readily incorporated into analytical and purification platforms
  • Suitable for glycoprotein detection, quantification, isolation and affinity purification
  • Applications include glycoform analysis, binding assays, lectin blotting, lectin arrays, ELLA, histochemical staining and bio-layer interferometry

Technical details

  • Manufacturer catalogue number: L-006-2mg
  • Glycan specificity: Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose
  • Pack size: 2 mg
  • Concentration: 2 mg/mL
  • Monomer MW: 13,130 Da Exists as dimer under physiological conditions (PBS, pH7.2).
  • Expression system: Escherichia coli
  • Affinity tag: polyhistidine
  • Research use only

Test principle

Specific recognition and binding of the stated glycan epitope
Key facts & specifications
Research areas
Glycobiology, glycan analysis, glycoprotein characterisation, bioanalytical assays, affinity purification
Also known as
RPL-αMan, recombinant prokaryotic lectin, RPL, Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose
Tag
Polyhistidine tag
Modification
Recombinant bacterial expression; no eukaryotic post-translational modification expected
Molecular weight
Monomer MW: 13,130 Da Exists as dimer under physiological conditions (PBS, pH7.2).
Concentration
2 mg/mL
Form / buffer
Liquid protein preparation
Activity
Specific binding to Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose
Receptor
Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal α-mannose
Quantity per pack
2 mg
Technical note
GlycoSeLect L-006-2mg; 2 mg; 2 mg/mL. Monomer MW: 13,130 Da | dimer under physiological conditions (PBS, pH7.2)..
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Glycan-binding application matrix

Evidence status by application and model.

Sample typeGlycan recognitionBinding assay
Purified glycans
Glycosylated proteins
Identifiers & database references
Manufacturer SKU
L-006-2mg
Frequently asked questions
Who manufactured this product?

This product is manufactured by GlycoSeLect and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

GlycoSeLect
£250.00£212.50