Manufactured by:Reed Biotech
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p18 Polyclonal Antibody

p18 polyclonal antibody; host Rabbit; reactivity Human, Mouse, Monkey

SKU:
ABM5032706-1
Manufacturer SKU
RA28312
Product type
Primary Antibodies
Targetp18
ApplicationsWB, IHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse, Monkey

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

cyclin dependent kinase inhibitor 2C(CDKN2C) Homo sapiens The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],

Key facts & specifications
Also known as
CDKN2C, CDKN6, Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6
Host species
Rabbit
Clonality
Polyclonal
Dilution range
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160
Molecular weight
18 kDa
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWBIHC-PIFELISA
Human,Mouse,Monkey
Identifiers & database references
Manufacturer SKU
RA28312
Gene ID
1031
UniProt accession
P42773
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

UBE2Iubiquitin conjugating enzyme E2 I

View target guide

UBE2I identifies ubiquitin conjugating enzyme E2 I in Homo sapiens (Human). This target record connects NCBI Gene 7329, UniProtKB P63279 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
7329
UniProtKB
P63279
Reed Biotech
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