Annexin II polyclonal antibody; host Rabbit; reactivity Human, Mouse, Rat
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annexin A2(ANXA2) Homo sapiens This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB | ELISA |
|---|---|---|
| Human,Mouse,Rat |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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Annexin A2 (ANXA2) is a calcium-dependent phospholipid-binding annexin family protein involved in membrane-associated processes, signal transduction and regulation of cellular growth.
Biological function: ANXA2 binds phospholipids in a calcium-dependent manner and participates in membrane organisation and signalling. NCBI describes annexin A2 family biology in cellular growth and signal-transduction pathways and identifies an autocrine role that can enhance osteoclast formation and bone resorption.
