Kit ELISA fourni par Boster Bio
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La métallopeptidase matricielle 9 (MMP-9) est également connue sous le nom de collagénase de type IV de 92 kDa, de gélatinase de 92 kDa ou de gélatinase B (GELB). Les collagénases de type IV de 72 et 92 kDa font partie d'un groupe de métalloprotéases zinc-dépendantes sécrétées. Les métalloprotéases matricielles (MMPs) sont capables de dégrader la matrice extracellulaire et de permettre l'angiogenèse et l'invasion tumorale. La MMP-9 est principalement exprimée dans les neutrophiles, les macrophages et les mastocytes, plutôt que dans les cellules néoplasiques oncogènes. Le polymorphisme de la MMP-9 agit comme un facteur génétique dans le développement de l'emphysème pulmonaire induit par le tabagisme.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum et plasma (héparine). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
MMP9 identifies matrix metallopeptidase 9 in Homo sapiens (Human). This target record connects NCBI Gene 4318, UniProtKB P14780 and related ABMIUM catalogue products.
Biological function: MMP9 is a matrix metalloproteinase that contributes to local extracellular-matrix proteolysis and leukocyte migration. It can cleave extracellular-matrix substrates including type IV and type V collagens.
