Kit ELISA fourni par Boster Bio
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La famille de l'Interleukine 1 est un groupe de 11 cytokines bêta-trèfle. L'Interleukine-1, produite principalement par les monocytes sanguins, assure la panoplie de réactions de l'hôte collectivement appelées réponse de phase aiguë. L'Interleukine-1 bêta (IL-1 bêta) est un puissant stimulateur de la résorption osseuse et a été impliquée dans la pathogenèse du renouvellement osseux élevé et de l'ostéoporose. L'IL-1 bêta appartient aux cytokines pro-inflammatoires, elle favorise l'adhésion des cellules cancéreuses et les métastases hépatiques en régulant à la hausse l'expression de la molécule d'adhésion des cellules vasculaires-1 (VCAM-1) sur l'endothélium sinusoïdal hépatique (HSE).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| lysats cellulaires | ||||
| sérum et plasma (héparine | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL1B identifies interleukin 1 beta in Homo sapiens (Human). This target record connects NCBI Gene 3553, UniProtKB P01584 and related ABMIUM catalogue products.
Biological function: IL1B encodes interleukin-1 beta, a potent pro-inflammatory cytokine that promotes innate and adaptive immune responses including neutrophil activation, T- and B-cell activation and Th17 differentiation. Mature IL-1 beta can also be released during pyroptotic inflammation.
