Manufactured by:Promab
RUO

Anti-DEFA3 Rabbit Polyclonal Antibody

DEFA3 antibody from Promab.

SKU:
ABM421326-1
Product type
Primary antibodies
TargetDEFA3
ApplicationsWB, IHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.

For research use only.

Key facts & specifications
Also known as
DEF3; Neutrophil defensin 3; Defensin alpha 3; HNP-3; HP-3; DEFA3
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Defensin alpha 3. The exact sequence is proprietary.
Molecular weight
11 kD
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
DEFA3
Gene ID
1668
UniProt accession
P59666
Ensembl
ENSG00000239839
HGNC
2762
OMIM
604522
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20