CTSD antibody from Promab.
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Acid protease active in intracellular protein breakdown. CTSD plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. CTSD is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||
| Mouse | |||||||||
| Rat |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Cathepsin D (CTSD) is a lysosomal aspartic protease involved in intracellular protein breakdown. This target hub connects the accepted name and identifiers with ABMIUM antibodies, ELISA kits and related research products.
Biological function: Cathepsin D (CTSD) is an acid-active lysosomal aspartic protease involved in intracellular protein breakdown. The precursor is proteolytically processed to mature light and heavy chains, and the enzyme contributes to lysosomal proteolysis and protein turnover.
