ARSA antibody from Promab.
Know who made it. See the evidence. Buy through one marketplace.
Lysosomal enzyme that catalyses the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein saposin B. Also involved in the catabolism of other sulfoglycosphingolipids such as SB1a and SM3 (beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine).
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||
| Mouse | |||||||||
| Rat |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ARSA encodes arylsulfatase A, also known as ASA, a lysosomal sulfatase that degrades cerebroside-3-sulfate (sulfatide). The enzyme is a key component of lysosomal glycosphingolipid catabolism. Abmium catalogue products linked below support research into ARSA expression, lysosomal function and sulfatide metabolism.
Biological function: Arylsulfatase A is a lysosomal hydrolase that catalyses cleavage of sulfate from cerebroside-3-sulfate, producing cerebroside and sulfate; the reaction requires saposin B. This activity supports turnover of sulfatides and normal lysosomal lipid metabolism. Reduced ARSA activity causes sulfatide accumulation, making the enzyme a central mechanistic target in metachromatic leukodystrophy research.
