Manufactured by:ProteoGenix
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Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade

Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade from ProteoGenix; catalogue PX-TA2092; research use only.

SKU:
ABM133971-1
Manufacturer SKU
PX-TA2092
Product type
Primary Antibodies
TargetUlviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>90% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade is a novel biosimilar antibody that has been developed for targeting CLEC15A, a key therapeutic target in various diseases. This antibody has been designed to mimic the structure and activity of the original CLEC15A antibody, while providing a more cost-effective and accessible option for researchers and clinicians. In this article, we will explore the structure, activity, and potential applications of Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade.

Structure of Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade

Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade is a monoclonal antibody (mAb) that is produced by cloning a single B cell that has been stimulated to produce a specific antibody. This mAb is a recombinant protein that is composed of two light chains and two heavy chains, each containing a variable region and a constant region. The variable region is responsible for binding to the target antigen, CLEC15A, while the constant region provides stability and effector functions.

Activity of Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade

The primary activity of Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade is to specifically bind to CLEC15A, a protein that is expressed on the surface of various cells, including immune cells and cancer cells. By binding to CLEC15A, this antibody can block its interaction with other proteins, thus inhibiting downstream signaling pathways that are involved in disease progression. Additionally, Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade can also induce antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), leading to the destruction of CLEC15A-expressing cells.

Applications of Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade

Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade has potential applications in various diseases where CLEC15A is implicated, including cancer, autoimmune disorders, and infectious diseases. In cancer, CLEC15A has been shown to promote tumor growth and metastasis, making it an attractive target for cancer therapy. By blocking CLEC15A with Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade, it may be possible to inhibit tumor growth and metastasis, as well as sensitize cancer cells to other treatments.

In autoimmune disorders, CLEC15A has been linked to the development of inflammatory responses, making it a potential therapeutic target. By targeting CLEC15A with Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade, it may be possible to attenuate the inflammatory response and reduce the severity of autoimmune diseases.

In infectious diseases, CLEC15A has been shown to play a role in the immune response to viral and bacterial infections. By blocking CLEC15A with Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade, it may be possible to enhance the immune response and improve the clearance of pathogens.

Conclusion

In summary, Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade is a novel biosimilar antibody that specifically targets CLEC15A, a key therapeutic target in various diseases. This antibody has a similar structure and activity to the original CLEC15A antibody and has potential applications in cancer, autoimmune disorders, and infectious diseases. With its cost-effective and accessible nature, Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade has the potential to make a significant impact in the field of therapeutics.

ProteoGenix catalogue number PX-TA2092. For research use only.

Target: Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.

Available configurations: 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
anti-CLEC15A, Mast cell function-associated antigen, Killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, MAFA, KLRG1, MAFA-like receptor, ITIM-containing receptor MAFA-L, MAFAL
Clonality
Monoclonal
Isotype
IgG1-kappa
Source organism
Human
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Ulviprubart Biosimilar – Anti-CLEC15A mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2092
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£159.00£127.20