Manufactured by:ProteoGenix
Save 20%RUO

Tinurilimab Biosimilar – Anti-CEACAM6 mAb – Research Grade

Tinurilimab Biosimilar – Anti-CEACAM6 mAb – Research Grade from ProteoGenix; catalogue PX-TA1609; research use only.

SKU:
ABM134437-1
Manufacturer SKU
PX-TA1609
Product type
Primary Antibodies
TargetTinurilimab Biosimilar – Anti-CEACAM6 mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction:

Tinurilimab Biosimilar, also known as Anti-CEACAM6 mAb, is a research grade monoclonal antibody that has shown promising results in targeting a specific protein known as CEACAM6. This article will provide a detailed scientific description of the structure, activity, and potential applications of Tinurilimab Biosimilar as an antibody therapy.

Structure of Tinurilimab Biosimilar:

Tinurilimab Biosimilar is a monoclonal antibody, meaning it is produced by identical immune cells and is designed to target a specific antigen. The structure of Tinurilimab Biosimilar is composed of two identical heavy chains and two identical light chains, connected by disulfide bonds. The heavy chains consist of a constant region and a variable region, while the light chains contain only a variable region. The variable regions are responsible for binding to the target antigen, CEACAM6, while the constant regions provide stability and effector functions.

Activity of Tinurilimab Biosimilar:

The primary activity of Tinurilimab Biosimilar is its ability to bind to CEACAM6, a cell surface protein that is overexpressed in many types of cancer. This binding is highly specific and allows Tinurilimab Biosimilar to selectively target cancer cells while sparing healthy cells. Once bound to CEACAM6, Tinurilimab Biosimilar can trigger various immune responses, such as antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), leading to the destruction of cancer cells.

In addition to its direct activity against

cancer cells, Tinurilimab Biosimilar also has the potential to modulate the tumor microenvironment. CEACAM6 has been shown to play a role in promoting tumor growth and metastasis, and by targeting this protein, Tinurilimab Biosimilar may help to inhibit these processes.

Applications of Tinurilimab Biosimilar:

Tinurilimab Biosimilar has the potential to be used in a variety of applications, particularly in the field of oncology. As a monoclonal antibody, it can be used as a targeted therapy for various types of cancer, including lung, breast, and colorectal cancer. It may also be effective in combination with other cancer treatments, such as chemotherapy or immunotherapy.

In addition to its potential as a cancer therapy, Tinurilimab Biosimilar may also have applications in autoimmune diseases. CEACAM6 has been implicated in the development of autoimmune disorders, and by targeting this protein, Tinurilimab Biosimilar may help to alleviate symptoms and slow disease progression.

Conclusion:

In conclusion, Tinurilimab Biosimilar is a research grade monoclonal antibody with a specific structure and activity. Its primary function is to bind to the cell surface protein CEACAM6 and trigger immune responses against cancer cells. It has the potential to be used in a variety of applications, including as a targeted therapy for cancer and in the treatment of autoimmune diseases. Further research and clinical trials are needed to fully explore the potential of Tinurilimab Biosimilar as a therapeutic antibody.

ProteoGenix catalogue number PX-TA1609. For research use only.

Target: Tinurilimab Biosimilar – Anti-CEACAM6 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg, 10mg, 25mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
Tinurilimab ,BAY-1834942,CEACAM6,anti-CEACAM6
Clonality
Monoclonal
Isotype
IgG1, kappa
Source organism
Humanized
Sequence
MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Tinurilimab Biosimilar – Anti-CEACAM6 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1609
UniProt accession
P40199
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£85.00£68.00