Manufactured by:ProteoGenix
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Telimomab Biosimilar – Anti-CD5 mAb – Research Grade

Telimomab Biosimilar – Anti-CD5 mAb – Research Grade from ProteoGenix; catalogue PX-TA1229; research use only.

SKU:
ABM134813-1
Manufacturer SKU
PX-TA1229
Product type
Primary Antibodies
TargetTelimomab Biosimilar – Anti-CD5 mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Telimomab Biosimilar – Anti-CD5 mAb – Research Grade

Telimomab Biosimilar – Anti-CD5 mAb – Research Grade: A Promising Antibody for Therapeutic Targeting

Introduction

Telimomab Biosimilar – Anti-CD5 mAb – Research Grade is a monoclonal antibody (mAb) that has shown great potential in the field of immunotherapy. It is a biosimilar version of Telimomab, a therapeutic antibody that targets the CD5 antigen. This biosimilar form offers a more cost-effective and accessible option for researchers and clinicians to study and utilize in their work.

Structure of Telimomab Biosimilar

Telimomab Biosimilar is a recombinant, humanized mAb that is produced in a mammalian cell expression system. It is composed of two identical heavy chains and two identical light chains, each with a molecular weight of approximately 150 kDa. The heavy and light chains are connected by disulfide bonds and form a Y-shaped structure. The variable regions of the antibody are responsible for binding to the CD5 antigen, while the constant regions mediate effector functions.

Activity of Telimomab Biosimilar

Telimomab Biosimilar specifically targets the CD5 antigen, a glycoprotein that is expressed on the surface of T cells and B cells. CD5 is involved in the regulation of T and B cell activation and differentiation. It is also overexpressed in certain types of cancer cells, making it a potential therapeutic target for cancer treatment.

By binding to the CD5 antigen, Telimomab Biosimilar blocks its function and inhibits the activation and proliferation of T and B cells. This can be beneficial in autoimmune diseases, where the immune system is overactive and attacking healthy cells. It can also be used in cancer treatment, as it can induce cell death in CD5-expressing cancer cells.

Application of Telimomab Biosimilar

Telimomab Biosimilar has several potential applications in the field of immunotherapy. It can be used as a treatment for autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By targeting CD5-expressing cells, it can help reduce inflammation and prevent further damage to tissues and organs.

In cancer treatment, Telimomab Biosimilar can be used as a targeted therapy for CD5-positive cancers, including T-cell lymphomas, chronic lymphocytic leukemia, and B-cell lymphomas. It can be used alone or in combination with other treatments to enhance its efficacy.

Furthermore, Telimomab Biosimilar can also be used as a research tool in the development of new therapies and in the study of the CD5 antigen and its role in various diseases. Its biosimilar form allows for easier access and affordability for researchers, making it a valuable resource in the scientific community.

Conclusion

Telimomab Biosimilar – Anti-CD5 mAb – Research Grade is a promising antibody with potential applications in the treatment of autoimmune diseases and cancer. Its specific targeting of the CD5 antigen makes it a valuable tool in immunotherapy and research. With its cost-effective biosimilar form, it offers a more accessible option for scientists and clinicians to utilize in their work. Further studies and clinical trials are needed to fully explore the potential of this antibody and its role in improving human health.

ProteoGenix catalogue number PX-TA1229. For research use only.

Target: Telimomab Biosimilar – Anti-CD5 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
Telimomab,T101-ricin A chain immunotoxin,T101-RTA,CD5 ,anti-CD5
Clonality
Monoclonal
Isotype
Fab-nd-nd
Source organism
Mouse
Sequence
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPDNSSDSDYDLHGAQRL
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Telimomab Biosimilar – Anti-CD5 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1229
UniProt accession
P06127
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20