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Recombinant Human DCTN6 Protein, N-His

Recombinant Human DCTN6 Protein, N-His from ProteoGenix; catalogue ARO-P11583; research use only.

SKU:
ABM142022-1
Manufacturer SKU
ARO-P11583
Product type
Recombinant Proteins
Expression systemProkaryotic expression

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Recombinant Human DCTN6 Protein

Recombinant Human DCTN6 Protein, also known as Dynactin Subunit 6, is a protein that plays a crucial role in the assembly and function of the dynactin complex. This protein is encoded by the DCTN6 gene and is a subunit of the dynactin complex, which is involved in intracellular transport and organization of the cytoskeleton. Recombinant Human DCTN6 Protein is an important tool in scientific research and has various applications in the fields of cell biology, biochemistry, and medicine.

Structure of Recombinant Human DCTN6 Protein

Recombinant Human DCTN6 Protein is a 50 kDa protein consisting of 460 amino acids. It contains a coiled-coil domain at the N-terminus and a globular domain at the C-terminus. The coiled-coil domain is responsible for protein-protein interactions, while the globular domain is involved in binding to microtubules. This unique structure allows Recombinant Human DCTN6 Protein to interact with other proteins and play a crucial role in the formation of the dynactin complex.

Activity of Recombinant Human DCTN6 Protein

Recombinant Human DCTN6 Protein is a key component of the dynactin complex, which is essential for the transport of cellular cargo along microtubules. It acts as a linker between the microtubule motor protein dynein and its cargo, allowing for efficient movement of cellular materials. In addition, Recombinant Human DCTN6 Protein is involved in the organization and stabilization of the microtubule network, which is important for maintaining cell structure and shape.

Application of Recombinant Human DCTN6 Protein

Recombinant Human DCTN6 Protein has a wide range of applications in scientific research. One of its main uses is in the study of the dynactin complex and its role in intracellular transport. By manipulating the expression or function of Recombinant Human DCTN6 Protein, researchers can gain a better understanding of the mechanisms involved in cellular transport and organization.

In addition, Recombinant Human DCTN6 Protein can also be used as an antigen in various immunological studies. Its unique structure and function make it a potential target for the development of vaccines or therapeutic antibodies. Furthermore, Recombinant Human DCTN6 Protein can be used in drug discovery and development, as it is involved in various cellular processes that are potential targets for pharmaceutical interventions.

Another important application of Recombinant Human DCTN6 Protein is in the field of cancer research. Alterations in the expression or function of the dynactin complex, including Recombinant Human DCTN6 Protein, have been linked to various types of cancer. By studying this protein, researchers can gain insights into the molecular mechanisms of cancer development and potentially identify new therapeutic targets.

Conclusion

In summary, Recombinant Human DCTN6 Protein is a crucial component of the dynactin complex and plays a vital role in intracellular transport and organization. Its unique structure and function make it a valuable tool in scientific research, with applications in cell biology, biochemistry, and medicine. Further studies on this protein may lead to a better understanding of cellular processes and the development of new treatments for various diseases.

ProteoGenix catalogue number ARO-P11583. For research use only.

Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 22.91 kDa; Fragment: Met1-Asn190; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Dynactin subunit p27, DCTN6, Protein WS-3, Dynactin subunit 6, WS3
Host species
E. coli
Source organism
Human
Molecular weight
22.91 kDa
Sequence fragment
Met1-Asn190
Sequence
MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN
Technical note
For research use only.
Identifiers & database references
Manufacturer SKU
ARO-P11583
UniProt accession
O00399
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Shipped at
Dry Ice
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
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