Manufactured by:ProteoGenix
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Ozureprubart Biosimilar – Anti-Ig epsilon chain C region mAb – Research Grade

Ozureprubart Biosimilar – Anti-Ig epsilon chain C region mAb – Research Grade from ProteoGenix; catalogue PX-TA2208; research use only.

SKU:
ABM133846-1
Manufacturer SKU
PX-TA2208
Product type
Primary Antibodies
TargetOzureprubart Biosimilar – Anti-Ig epsilon chain C region mAb – Research Grade
Expression systemXtenCHO
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction

Ozureprubart Biosimilar is a therapeutic antibody that specifically targets the Ig epsilon chain C region, also known as IgE. This biosimilar is a research grade antibody that has been developed to mimic the activity of existing IgE-targeting therapeutic antibodies. In this article, we will discuss the structure, activity, and potential applications of Ozureprubart Biosimilar in the field of immunology.

Structure of Ozureprubart Biosimilar

Ozureprubart Biosimilar is a monoclonal antibody, meaning it is produced by a single clone of cells. It is a recombinant antibody, meaning it is produced in a laboratory using genetic engineering techniques. The antibody is composed of two heavy chains and two light chains, each with a specific amino acid sequence. These chains come together to form a Y-shaped structure, with the two heavy chains making up the arms of the Y and the two light chains making up the stem.

The heavy chains of Ozureprubart Biosimilar contain a constant region, which is responsible for binding to immune cells and activating them, and a variable region, which is responsible for binding to the target antigen, IgE. The light chains also have a constant region and a variable region, with the variable region being responsible for binding to the target antigen.

Activity of Ozureprubart Biosimilar

Ozureprubart Biosimilar works by binding to IgE, a type of antibody that is involved in allergic reactions. By binding to IgE, Ozureprubart Biosimilar prevents it from binding to its target antigen, such as pollen or dust mites. This prevents the activation of immune cells, which would normally lead to the release of chemicals that cause allergy symptoms.

In addition to blocking the activity of IgE, Ozureprubart Biosimilar also has the ability to activate immune cells, such as natural killer cells and macrophages. This can help to enhance the body’s immune response against pathogens and cancer cells.

Potential Applications of Ozureprubart Biosimilar

The primary application of Ozureprubart Biosimilar is in the treatment of allergies. By targeting IgE, it can effectively reduce the symptoms of allergies, such as sneezing, itching, and swelling. It can also be used in combination with other allergy medications for a more comprehensive treatment approach.

In addition to allergies, Ozureprubart Biosimilar may also have potential applications in the treatment of autoimmune diseases. Some autoimmune diseases, such as asthma and eczema, are also associated with elevated levels of IgE. By targeting IgE, Ozureprubart Biosimilar may be able to reduce the severity of these diseases by preventing the activation of immune cells.

Another potential application of Ozureprubart Biosimilar is in cancer therapy. IgE has been shown to play a role in the growth and spread of certain types of cancer. By targeting IgE, Ozureprubart Biosimilar may be able to inhibit the growth and spread of these cancers, making it a promising therapy for cancer patients.

Conclusion

Ozureprubart Biosimilar is a promising therapeutic antibody that specifically targets IgE. Its unique structure and activity make it a potential treatment option for allergies, autoimmune diseases, and cancer. As research on this biosimilar continues, it may open up new possibilities for the treatment of various diseases and conditions.

ProteoGenix catalogue number PX-TA2208. For research use only.

Target: Ozureprubart Biosimilar – Anti-Ig epsilon chain C region mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-Ig epsilon chain C region, IGHE, Ig epsilon chain C region ND, Immunoglobulin heavy constant epsilon
Clonality
Monoclonal
Isotype
IgG1, kappa
Source organism
Human
Sequence
ASTQSPSVFPLTRCCKNIPSNATSVTLGCLATGYFPEPVMVTWDTGSLNGTTMTLPATTLTLSGHYATISLLTVSGAWAKQMFTCRVAHTPSSTDWVDNKTFSVCSRDFTPPTVKILQSSCDGGGHFPPTIQLLCLVSGYTPGTINITWLEDGQVMDVDLSTASTTQEGELASTQSELTLSQKHWLSDRTYTCQVTYQGHTFEDSTKKCADSNPRGVSAYLSRPSPFDLFIRKSPTITCLVVDLAPSKGTVNLTWSRASGKPVNHSTRKEEKQRNGTLTVTSTLPVGTRDWIEGETYQCRVTHPHLPRALMRSTTKTSGPRAAPEVYAFATPEWPGSRDKRTLACLIQNFMPEDISVQWLHNEVQLPDARHSTTQPRKTKGSGFFVFSRLEVTRAEWEQKDEFICRAVHEAASPSQTVQRAVSVNPGLAGGSAQSQRAPDRVLCHSGQQQGLPRAAGGSVPHPRCHCGAGRADWPGPPELDVCVEEAEGEAPWTWTGLCIFAALFLLSVSYSAAITLLMVQRFLSATRQGRPQTSLDYTNVLQPHA
Technical note
For research use only. Not suitable for human use.
Identifiers & database references
Manufacturer SKU
PX-TA2208
UniProt accession
P01854
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20